551 Atopic dermatitis in childhood and academic performance

Atopic dermatitis (AD) may affect academic performance,e.g., through poor attention due to itching. We examined this hypothesis in a binational study using data from linked nationwide Danish registries and English the Avon Longitudinal Study of Parents Children (ALSPAC) National Pupil Database. In Denmark, we included children birth cohorts 1986–2000 who were alive on their 13thbirth day. compared grade point average (GPA) ninth final exams Mathematics those with (n=12,824) vs. without (n=932,798) hospital inpatient or outpatient clinic diagnosis AD before age 13. GPA ranges -03 12; grades ≥02 are passing. England, enrolled ALSPAC between 1990–2009 at one followed repeated assessment until 11.5. proportion achieving ≥5 general certificates secondary education (GCSE) A*–C by 16 two reports (n=3,258) (n=4,319). 94% patients 95% unexposed attended all Maths, attaining mean combined 6.45 (SD 2.57) 6.52 2.53), respectively. A failing occurred 4.4% 3.8%. Results similar when siblings served as comparators. analysis, had 9.9% higher absolute probability GCSEs without. Multivariable regression stratified analyses parental socioeconomic position, severity, sex still ongoing. is associated performance but not Danish. Confounding modification severity factors explain differences.